Publications

Biosensors: An Overview of Detection of Environmental Pollutants Monitoring, Current Challenges, and Future Perspectives.
Sahadevan, R., Vijayan, V. N., Kannan, K., Bovas, N. A., Sadhukhan, S.*
In: Verma, P. (eds), Biotechnology for Environmental Sustainability. Interdisciplinary Biotechnological Advances. Springer, Singapore. 593-635 (2025)
Gene Modification and Omics Technology for Pollution Management.
Chathangad, S. N., Bovas, N. A., Kothari, M., Sadhukhan, S.*
In: Verma, P. (eds), Biotechnology for Environmental Sustainability. Interdisciplinary Biotechnological Advances. Springer, Singapore. 496-506 (2025)
Chemoproteomics in live bacteria identifies covalent interactome of epigallocatechin-3-gallate (EGCG) underlying its multimodal antibacterial mechanism.
Chathangad, S. N.; George, J. A.; Sahadevan, R.; Sadhukhan, S.*
J. Agric. Food Chem. Accepted (2025)
Design and synthesis of ibuprofen-based self-deliverable hybrid gel systems: Stabilization of silver nanoparticles, antibacterial and self-healing properties.
Bora, A.; Munjal, R.; Chakraborty, A.; Meena, L.; Chathangad, S. N.; Sadhukhan, S.; Mukhopadhyay, S.*
ACS Appl. Bio Mater. Accepted (2025)
Mitigating antimicrobial resistance through strategic design of multimodal antibacterial agents based on 1,2,3-triazole with Click chemistry.
Chathangad, S. N.; Vijayan, V. N.; George, J. A.; Sadhukhan, S.*
ACS Bio & Med Chem Au. Accepted (2025)
Dithiocarbamate-based sequence-defined oligomers as promising membrane-disrupting antibacterial agents: Design, activity, and mechanism.
Jose, A.; Chathangad, S. N.; Sivadas, P.; Barik, D.; Kannan, K.; Das, S.*; Sadhukhan, S.*; Porel, M.*
ACS Appl. Bio Mater. 8 1547 (2025)
Unraveling the potential contribution of DHHC2 in cancer biology via untargeted metabolomics.
Chaturvedi, S.; Karthik, S.S.; Sadhukhan, S.*; Sonawane, A.*
Biochim. Biophys. Acta: Mol. Cell Biol. Lipids 1870 159593 (2025)
Insights into one drug, multi-target aspects of polyphenols for diabetes management: In vitro, in vivo, and clinical evidence.
Kannan, K.; George, J. A.; Sahadevan, R.; Kothari, M.; Sadhukhan, S.*
Phytochem. Rev. Accepted (2024)
Lipophilic derivatives of EGCG as potent α-amylase and α-glucosidase inhibitors ameliorating oxidative stress and inflammation.
Kothari, M.; Kannan, K.; Sahadevan, R.; Retnakumar, S. V.; Chauvin, C.; Bayry, J.; Sadhukhan, S.*
Bioorg. Chem. 153 107786 (2024)
Membrane-active amphiphilic EGCG derivatives and their silver nanoparticles-formulation as broad-spectrum antibacterial and antibiofilm agents.
Chathangad, S. N.; Vijayan, V. N. ; Bovas, N. A. ; Sahadevan, R.; Sadhukhan, S.*
ACS Appl. Nano Mater. 7 18920–18931 (2024)
ε-Poly-L-lysine: A naturally-occurring biodegradable polypeptide for selective detection of 5-nitroimidazole antibiotics in animal products and living cells via fluorescence.
Vijayan, V. N.; Kannan, K.; Sahadevan, R.; Jose, A.; Porel, M.*; Sadhukhan, S.*
ACS Appl. Bio Mater. 7 4654 (2024)
Unconventional fluorescence behaviour of ε-polylysine: Selective and sensitive detection of Cu2+ in real water samples, test paper strips, living cells, and anticounterfeiting applications
Sahadevan, R.; Kannan, K.; Jose, A.; Porel, M.*; Sadhukhan, S.*
Sens. Actuators B Chem 409 135589 (2024)
Novel molecular hybrids of EGCG and quinoxaline: Potent multi-targeting antidiabetic agents that inhibit α-glucosidase, α-amylase, and oxidative stress
Kothari, M.; Kannan, K.; Sahadevan, R.; Sadhukhan, S.*
Int. J. Biol. Macromol. 263 130175 (2024)
Identification of selective plant-derived natural carotenoid and flavonoids as the potential inhibitors of DHHC-mediated protein S-palmitoylation: an in-silico study
Chaturvedi, S.; Pandya, N.; Sadhukhan, S.; Sonawane, A.*
J Biomol. Struct. Dyn. in press (2024)
Protein S-palmitoylation is markedly inhibited by 4"-alkyl ether lipophilic derivatives of EGCG, the major green tea polyphenol: In vitro and in silico studies
Binoy, A.; Kothari, M. ; Sahadevan, R. ; Poddar, S.; Kar, P.; Sadhukhan, S.*
Biochim. Biophys. Acta Biomembr. 1866 184264 (2024)
Selective luminescent detection of 5-nitroimidazole antibiotics through self-aggregates of a single non-aromatic amino acid, L-lysine
Jose, A.; Vijayan, V. N.; Sahadevan, R.; Porel, M.*; Sadhukhan, S.*
Microchem. J. 197 109802 (2024)
Pyrene aroylhydrazone-based Pd(II) complexes for DNA/protein binding, cellular imaging and in vitro anticancer activity via ROS production
Vignesh, A.; Binoy, A.; Thurakkal, L.; Bhuvanesh, N.S.P.; Sadhukhan, S.*; Porel, M.*
J. Mol. Struct. 1295 136693 (2024)
4"-Alkyl EGCG derivatives induce cytoprotective autophagy response by inhibiting EGFR in glioblastoma cells
Singh, S.; Ghosh, P.; Roy, R.; Behera, A.; Sahadevan, R.; Kar, P.; Sadhukhan, S.*; Sonawane, A.*
ACS Omega 9 2286 (2024)
Mitochondria-targeting EGCG derivatives protect H9c2 cardiomyocytes from H2O2-induced apoptosis: Design, synthesis and biological evaluation
Sahadevan, R. ; Binoy, A. ; Shajan, I.; Sadhukhan, S.*
RSC Adv. 13 29477 (2023)
20 years since the approval of first EGFR-TKIs, Gefitinib: Insight and foresight
Singh, S.; Sadhukhan, S.*; Sonawane, A.*
Biochim. Biophys. Acta: Rev. Cancer 1878 188967 (2023)

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