The Tampered Random Variable (TRV) model for multiple step-stress life
testing experiment is present in the literature for more than two stress levels.
However, the work emphasizes on the TRV modeling of data from multiple
Seminars
Department of Biological Sciences & Engineering: department Seminar
Venue: Online platform
Time: 10:30 AM
Date: 19 Jul 2023
Department of Biological Sciences & Engineering: department Seminar
Venue: Online platform
Time: 2:30 PM
Immunoglobulin light chain amyloidosis (AL) is caused by the aberrant production of
amyloidogenic light chains (LC) that accumulate as amyloid deposits in vital organs.
Distinct LC sequences in each patient yield distinct amyloid structures. Moreover,
different tissue microenvironments may also cause identical protein precursors to
adopt distinct amyloid structures. These reasons have contributed to the current
popular opinion that amyloid fibrils exhibit structural polymorphism. To address the


