Publications

Non-aromatic single amino acid, lysine: A simple fluorescence sensor for selective detection of Cu (II) and Co(II) with colorimetric distinction by the virtue of its self-aggregation behaviour
Sahadevan, R.; Jose, A.; Porel, M.*; Sadhukhan, S.*
J. Photochem. Photobiol. A Chem. 445 115086 (2023)
Role of EGFR and FASN in breast cancer progression
Chaturvedi, S.; Biswas, M.; Sadhukhan, S.*; Sonawane, A.*
J. Cell. Commun. Signal. 17 1249 (2023)
Design, synthesis, and applications of pyrene-quinoline based cell-permeable AIEgen for cellular imaging and antibacterial activity
Jose, A.; Chathangad, S. N.; Sahadevan, R.; Binoy, A.; Vignesh, A.; Sadhukhan, S.*; Porel, M.*
J. Photochem. Photobiol. A Chem. 444 114950 (2023)
In situ global proteomics profiling of EGCG targets using a cell-permeable and Click-able bioorthogonal probe
Sahadevan, R., Binoy, A., Vechalapu, S.K., Nanjan, P., Sadhukhan, S.*
Int. J. Biol. Macromol. 237 123991 (2023)
Dansyl appended sequence-defined oligomers for selective ultrasensitive detection of Hg2+ in water, paper strips, living cells and its efficient removal
Jose, A., Sahadevan, R., Vijay, M, Sadhukhan, S.*, Porel, M.*
Sens. Actuators B Chem 380 133335 (2023)
Chemico-biological aspects of (−)-epigallocatechin-3-gallate (EGCG) to improve its stability, bioavailability and membrane permeability: Current status and future prospects
Revathy Sahadevan, Satyam Singh, Anupama Binoy, Sushabhan Sadhukhan*
Crit. Rev. Food. Nutr. Sci. 63 10382 (2023)
A novel 4"-alkyl ether derivative of green tea polyphenol EGCG as potent and selective EGFR inhibitor: In-vitro and in-silico studies
Satyam Singh, Revathy Sahadevan, Rajarshi Roy, Mainak Biswas, Priya Ghosh, Parimal Kar, Avinash Sonawane, Sushabhan Sadhukhan*
RSC Adv. 12 17821 (2022)
Pharmacological and genetic perturbation establish SIRT5 as a promising target in breast cancer
Yashira L. Negrón Abril, Irma R. Fernandez, Jun Young Hong, Ying-Ling Chiang, Dennis A. Kutateladze, Qingjie Zhao, Min Yang, Jing Hu, Sushabhan Sadhukhan, Bo Li, Bin He, Brenna Remick, Jessica Jingyi Bai, James Mullmann,.... Hening Lin, Robert S. Weiss.
Oncogene 40 1644–1658 (2021)
An in-silico study on selected organosulfur compounds as potential drugs for SARS-CoV-2 infection via binding multiple drug targets
Liya Thurakkal, Satyam Singh, Rajarshi Roy, Parimal Kar, Sushabhan Sadhukhan*, Mintu Porel*
Chem. Phys. Lett. 763 138193 (2021)
Plant-derived natural polyphenols as potential antiviral drugs against SARS-CoV-2 via RNA‐dependent RNA polymerase (RdRp) inhibition: An in-silico analysis
Satyam Singh, Md Fulbabu Sk, Avinash Sonawane, Parimal Kar, Sushabhan Sadhukhan*
J. Biomol. Struct. Dyn. 39 (16) 6249-6264 (2021)
Direct Comparison of SIRT2 Inhibitors: Potency, Specificity, Activity-dependent Inhibition, and On-target Anticancer Activities
Nicole A. Spiegelman, Ian R. Price, Hui Jing, Miao Wang, Min Yang, Ji Cao, Jun Young Hong, Xiaoyu Zhang, Pornpun Aramsangtienchai, Sushabhan Sadhukhan, and Hening Lin.
ChemMedChem. 13 1890-1894 (2018)
Emerging Roles of DHHC-mediated Protein S-palmitoylation in Physiological and Pathophysiological Context
Indranil De, Sushabhan Sadhukhan*
Euro. J. Cell Biol. 97 319-338 (2018)
SIRT7 Is an RNA-activated Protein Lysine Deacylase
Zhen Tong, Miao Wang, Yi Wang, David D. Kim, Jennifer K. Grenier, Ji Cao, Sushabhan Sadhukhan, Quan Hao, and Hening Lin.
ACS Chem. Biol. 12 300-310 (2017)
SIRT7 Is Activated by DNA and Deacetylates Histone H3 in the Chromatin Context
Zhen Tong, Yi Wang, Xiaoyu Zhang, David D. Kim, Sushabhan Sadhukhan, Quan Hao, and Hening Lin.
ACS Chem. Biol. 11 742-747 (2016)
Metabolomics-assisted Proteomics Identifies Succinylation and SIRT5 as Important Regulators of Cardiac Function
Sushabhan Sadhukhan, Xiaojing Liu, Dongryeol Ryu, Ornella Nelson, John Stupinski, Zhi Li, Wei Chen, Sheng Zhang, Robert Weiss, Jason Locasale, Johan Auwerx, and Hening Lin.
Proc. Natl. Acad. Sci. USA. 113 4320-4325 (2016)
High Resolution Metabolomics With Acyl-CoA Profiling Reveals Widespread Remodeling In Response To Diet
Xiaojing Liu, Sushabhan Sadhukhan, Shengyi Sun, Gregory R. Wagner, Matthew D. Hirschey, Ling Qi, Hening Lin, and Jason W. Locasale.
Mol. Cell. Proteomics 14 1489-1500 (2015)
Identification of a Negative Feedback Loop in Biological Oxidant Formation Regulated by 4-Hydroxy-2-(E)-Nonenal
Tonibelle N. Gatbonton-Schwager, Sushabhan Sadhukhan, Guo-Fang Zhang, John J. Letterio, and Gregory P. Tochtrop.
Redox Biol. 2 755-763 (2014)
Glutathionylated 4-Hydroxy-2-(E)-Alkenal Enantiomers in Rat Organs and Its Contributions Towards the Disposal of 4-Hydroxy-2-(E)-Nonenal in Rat Liver
Sushabhan Sadhukhan, Yong Han, Zhicheng Jin, Gregory P. Tochtrop, and Guo-Fang Zhang.
Free Rad. Biol. Med. 70 78-85 (2014)
Modular Isotopomer Synthesis of γ-Hydroxybutyric Acid for a Quantitative Analysis of Metabolic Fates
Sushabhan Sadhukhan, Guo-Fang Zhang, and Gregory P. Tochtrop.
ACS Chem. Biol. 9 1706-1711 (2014)
Catabolism of 4-Hydroxy-2-(E)-Nonenal via Omega- and Omega-1 Oxidation: Stimulated by Ketogenic Diet
Zhicheng Jin, Jessica M. Berthiaume, Qingling Li, Fabrice Henry, Zhong Huang, Sushabhan Sadhukhan, Peng Gao, Gregory P. Tochtrop, Michelle A. Puchowicz and Guo-Fang Zhang.
J. Biol. Chem. 289 32327-32338 (2014)